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Clinical Trial Success

Tuesday, January 14th, 2025

Data from a clinical trial shows that a dual immunotherapy regimen plus short-course radiation for the treatment of rectal cancer that is microsatellite instability-high (MSI-H) or mismatch repair deficient (dMMR) can be effective enough to avoid chemotherapy and colostomy-requiring surgery.  The data from the EA2201 study was so promising that the clinical trial is being […]

Colorectal Cancer

Tuesday, January 14th, 2025

The Robert J. Kleberg, Jr. and Helen C. Kleberg Foundation has awarded a $1 million grant to support research at Vanderbilt aimed at dramatically expanding the efficacy of immunotherapy for colorectal cancer.    Currently, only people with microsatellite instability-high colorectal cancer, which accounts for about 10% of patients, respond to immune checkpoint inhibitors, but Vanderbilt researchers have […]

Preventive Treatment

Tuesday, January 14th, 2025

Years of research by Vanderbilt University Medical Center investigators to determine how precancerous cells in the stomach transition to gastric cancer and to develop strategies to prevent this transition have received federal funding to test two potential treatments.  The $2.5 million Department of Defense Translational Team Science Award provides funding over four years to launch a […]

Hospital Expansion Honors Jim Ayers

Tuesday, January 14th, 2025

Vanderbilt University Medical Center will name the new expansion tower for Vanderbilt University Hospital the Jim Ayers Tower in recognition of Janet and Jim Ayers’ philanthropic legacy and abiding interest in improving the health care and quality of life for Tennesseans. The naming of the 15-level, 470,000-square-foot tower, currently under construction between 21st Avenue South […]

Q+A: Scalp Cooling

Tuesday, January 14th, 2025

Q How does scalp cooling mitigate hair loss during chemotherapy? A Scalp cooling prevents chemotherapy-induced alopecia in two ways. First, it reduces blood flow to the scalp. Cooling causes the blood vessels in the scalp to constrict, which reduces the amount of medication reaching the follicles. Secondly, when our scalp’s temperature is lowered, our metabolism is […]

Journal Watch

Tuesday, January 14th, 2025

Only half of young cancer patients report discussingfertility preservation Only half of people with early-onset cancers reported discussing fertility preservation options prior to their oncology treatments, according to results of a cross-sectional study published Nov. 12, 2024, in JAMA Network Open. Young patients with thyroid, lung, ovarian and colorectal cancers reported the lowest prevalence of […]

Innovations: CAR-T Discoveries

Tuesday, January 14th, 2025

Remarkable. That’s how Bhagirathbhai Dholaria, MD, described responses to an ongoing clinical trial for patients with relapsed or refractory multiple myeloma who had run out of treatment options.  Dholaria, associate professor of Medicine, presented interim results from the Phase 1 trial for a new “off-the-shelf” chimeric antigen receptor-T cell (CAR-T) therapy at the 21st International […]

Clip In 4 the Cure

Tuesday, January 14th, 2025

Clip In 4 the Cure 2024 brought people together on Sept. 14, 2024, for an inspiring day of cycling and raising money for cancer research. This year’s event was the most successful yet, with more than 400 attendees at GEODIS Park and over $277,000 raised. This support makes a tangible impact on adult and pediatric […]

Glioma Warriors

Tuesday, January 14th, 2025

On a sunny June day, Olivia Leow was driving her sons to a friend’s swimming pool when she briefly lost her peripheral vision. Later that afternoon, while watching them splash about in the water, her right hand temporarily went numb.  After some online research that evening with her husband, she figured she had experienced an […]

Chemo Allergy

Tuesday, January 14th, 2025

A true allergy to a medication is not that common, and when it happens, there’s often a work-around, like substituting a drug in another class.  But what if you’re a patient with cancer and the drug you’re allergic to is a chemotherapy agent that offers the best, and sometimes only, chance of saving your life?  […]

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