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News: Journal Watch

Journal Watch

Tuesday, May 22nd, 2018

Novel anti-cancer drug resistance mechanism identified Vanderbilt investigators have discovered a novel nongenetic cause of resistance to cetuximab, a mainstay of treatment for advanced colorectal cancer. The findings of Robert Coffey Jr., MD, and colleagues, published Oct. 16, 2017, in Nature Medicine, suggest a strategy for overcoming this resistance, which their research indicates is due […]

Journal Watch

Wednesday, November 22nd, 2017

New target for colorectal cancer  In a study published March 6 in the journal Oncogene, Dana Hardbower, Ph.D., Keith Wilson, M.D., and colleagues demonstrated that epidermal growth factor receptor (EGFR) signaling in macrophages is associated with increased colitis-associated colon cancer development. While inflammatory bowel disease and colitis can increase the risk of colon cancer, the […]

Journal Watch

Wednesday, May 31st, 2017

Discovery offers new insight on lung cancer risk Researchers have discovered a proteomic “signature” from the airways of heavy smokers that could lead to better risk assessment and perhaps new ways to stop lung cancer before it starts. The findings, reported Nov. 17, 2016, in JCI Insight, are based on the observation that otherwise normal-looking […]

Journal Watch

Tuesday, December 6th, 2016

VUMC study: current cancer drug discovery method flawed The primary method used to test compounds for anti-cancer activity in cells is flawed, Vito Quaranta, M.D., and colleagues reported May 2 in Nature Methods. The scientists developed a new metric to evaluate a compound’s effect on cell proliferation. The old system counted how many cancer cells […]

Recent Publications by VICC Researchers

Thursday, June 2nd, 2016

Study identifies new culprit in lung cancer development A microRNA—a small piece of RNA involved in regulating gene expression—functions as an oncogene to drive the development of lung cancer, Vanderbilt-Ingram Cancer Center investigators have discovered. The microRNA, known as miR-31, is expressed at high levels in human lung adenocarcinoma, and its expression correlates with reduced […]

Recent Publications by VICC Researchers

Wednesday, January 27th, 2016

Protein identified as potential target for lung cancer treatment A protein that transports the amino acid glutamine is a potential biomarker and therapeutic target for non-small cell lung cancer, Vanderbilt-Ingram Cancer Center researchers reported in the Oct. 1, 2015, International Journal of Cancer. Pierre Massion, M.D., Cornelius Vanderbilt Chair in Medicine, and colleagues demonstrated that […]

Recent Publications by VICC Researchers

Monday, June 15th, 2015

Vanderbilt-Ingram Cancer Center is committed to conducting innovative, high-impact, basic, translational and clinical research with the greatest potential for making a difference for cancer patients, today and in the future. Here’s a sampling of work published in peer-reviewed journals by Cancer Center investigators in 2014-2015:   Study in East Asians identifies genes tied to colon […]

Recent Publications by VICC Researchers

Thursday, December 18th, 2014

Vanderbilt-Ingram Cancer Center is committed to conducting innovative, high-impact, basic, translational and clinical research with the greatest potential for making a difference for cancer patients, today and in the future. Here’s a sampling of work published in peer-reviewed journals by Cancer Center investigators in 2014:   Gene study focuses on breast cancer in East Asian […]

Recent Publications by VICC Researchers

Wednesday, May 21st, 2014

Vanderbilt-Ingram Cancer Center is committed to conducting innovative, high-impact, basic, translational and clinical research with the greatest potential for making a difference for cancer patients, today and in the future. Here’s a sampling of work published in peer-reviewed journals by Cancer Center investigators in 2013-2014:   Study sheds light on DNA replication During the more […]

Recent Publications by VICC Researchers

Thursday, November 21st, 2013

Vanderbilt-Ingram Cancer Center is committed to conducting innovative and high-impact basic, translational and clinical research with the greatest potential for making a difference for cancer patients, today and in the future. Here’s a sampling of work published in peer-reviewed journals by Cancer Center investigators in 2012-2013:   Study identifies new mechanism for cancer development Bhuminder […]

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